Autonomic Nervous System Control of Leukocyte Distribution: Physiology and Implications for Common Human Diseases

Leukocytes are key components of the body’s defense system and the major subsets of leukocytes are granulocytes and lymphocytes. We and others have found that the distribution of these subsets are under the regulation of the autonomic nervous system. Of note, granulocytes express adrenergic receptors and the number and proportion of granulocytes increase by a stimulation of the sympathetic nervous system. Indeed, there are several physiological variations of leukocytes, including neonatal granulocytosis, due to the sympathetic nerve activation by the … Continue reading Autonomic Nervous System Control of Leukocyte Distribution: Physiology and Implications for Common Human Diseases