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BrainImmune InterfaceBrainImmune is a free and independant online resource of expert views, opinions, comments and evolving concepts in neuroendocrine immunology. Our goal is to advance a new field in medical science that has great potential and significance.

BrainImmune is the only web resource that delivers up to date information into the broad interdisciplinary area of neuroendocrine-immunology and stress-immune interactions, and their impact on health and disease. Here, concise summaries and overviews describe how the brain and the immune system ‘talk to each other’ in order to maintain homeostasis.

We bring the latest developments in neuroendocrine immunology, reviewing new and advanced conceptual frameworks, and covering both the fundamental and clinical aspects in this vast interdisciplinary area.

Our resource draws together concepts and ideas scattered in hundreds of scientific journals and derived from thousands of articles that impinge in some way on integrative neuroendocrine immunology and immunophysiology.


The brain and the immune system, or the ‘supersystems’ (T. Tada, 1997), are the two major adaptive systems of the body. One of the paradoxes of medical sciences is building boundaries between disciplines and drawing dividing lines between research fields.

The immune system has been often regarded as autonomous, and the question of how the brain communicates with the immune system remained enigmatic until fairly recently. The more we share knowledge, the easier it is to break down barriers between scientific areas.

STRESS and Stress-Immune Interactions

According to the American Institute of Stress, ‘stress’ is America’s #1 health problem, whereas two-thirds of all office visits to family physicians are due to stress-related symptoms (cf. the American Academy of Family Physicians). BrainImmune is the first site covering stress-immune interactions with over 120 articles in this area.


Concepts discussed here represent recent advances in the field; they are not available in medical textbooks, and, as a general rule, not taught at medical schools. Thus, the BrainImmune resource might serve not only as a useful foundation of knowledge for researchers & medical professionals, but also as an important educational tool for medical & PhDs students or postdoctoral research scientists and trainees worldwide.


BrainImmune’s aim is to narrow the information and conceptual gap at the interface of neurosciences and immunology. Our mission is to promote the progress, communication and collaborations in neuroendocrine immunology and stress-immunity research, and to speed up innovation in this vast interdisciplinary area.

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