Commentary On Glymphatic failure as a final common pathway to dementia, Science, 2020; 370, pp. 50-56 While bound to desk work during home office, many of us have experienced swollen legs at the end of the day. This type of peripheral edema...
EDITORIALS & OPINION | COMMENTARIES
We have determined that enhanced expression of the pro-inflammatory cytokine Tumor Necrosis Factor (TNF)-α by both neurons and glial cells of the brain direct the process involved with the development and also the maintenance of neuropathic pain. However, TNF is not only a pro-inflammatory cytokine...
STRESS & IMMUNITY
Rheumatoid arthritis (RA) is an autoimmune condition characterized by chronic inflammation occurring locally within the synovial joints and systemically. Accumulating evidence supports an important role of the sympathetic nervous system in the pathophysiology of RA, both as a cause and consequence of inflammation. Acute sympathetic activation results in a shift from a T-helper (Th) 1 to Th2 response to direct the immune response towards the synovial joint thereby limiting systemic...
FEATURES & FACES