thymus

An Enterovirus Attacking the Thymus May Play a Key Role in Triggering Type 1 Diabetes

An Enterovirus Attacking the Thymus May Play a Key Role in Triggering Type 1 Diabetes

As part of the European FP6 Eurothymaide project, and, in close collaboration with Lille’s CHRU hospital (Didier Hober), the Centre d’Immunologie de Marseille-Luminy (Philippe Naquet) and the University of Tunis, Vincent Geenen and his team have discovered that infection of the thymus by the diabetogenic CV-B4 virus leads to a decrease in the transcription of […]

Oxytocin and Williams Syndrome: Exploring Neurobiology of Social Behavior

Oxytocin and Williams Syndrome: Exploring Neurobiology of Social Behavior

Commentary on the study by Li Dai et al., PLoS One. 2012;7(6):e38513 Oxytocin and Vasopressin Are Dysregulated in Williams Syndrome, a Genetic Disorder Affecting Social Behavior Quote from the original paper’s abstract “Results revealed significantly higher median levels of oxytocin (OT) in Williams syndrome (WS) versus controls at baseline, with a less marked increase in arginine […]

Thymus Emergence & Evolution of Immune and Neuroendocrine Systems

Thymus Emergence & Evolution of Immune and Neuroendocrine Systems

Editorials & Opinion Galen (129 – 210 or 216 AD) first described an organ located behind the sternum and named it ‘thymus’ because of its close resemblance with a leaf of the thyme plant. For Galen, the thymus was the ‘seat of soul, eagerness, and fortitude’, and this old misconception most probably explains why some […]

Growth Hormone (GH) Replacement and Thymus Function

Growth Hormone (GH) Replacement and Thymus Function

A recent PLoS One study by Gabriel Morrhaye et al., demonstrates that the functional integrity of the somatotrope growth hormone/insulin-like growth factor-1 axis is important for the maintenance of a normal thymus function in human adults. The secretion of growth hormone (GH) declines with aging until only low levels can be detected in individuals aged […]