t regulatory cells and nervous system

Melatonin May Control the Balance between Pathogenic Th17 and Regulatory T Cells

Melatonin May Control the Balance between Pathogenic Th17 and Regulatory T Cells

Commentary on the study by Mauricio Farez et al., 2015, Cell, 162, 1338–1352 Melatonin Contributes to the Seasonality of Multiple Sclerosis Relapses‘ The central master circadian clock is located in the suprachiasmatic nucleus (SCN). The output of this system is synchronized to 24 hours by the light-dark cycle. The SCN regulates rhythms in peripheral cells via […]

Influence of the Sympathetic Nervous System on Regulatory T cells: Another Link in Neuro-Immune Interactions

Influence of the Sympathetic Nervous System on Regulatory T cells: Another Link in Neuro-Immune Interactions

Overview article Homeostatic control of the immune system is dependent on CD4, FoxP3+, NKT or antigen-specific CD4+ or CD8+ regulatory T cells. These regulatory T cells are essential to prevent or mitigate autoimmunity and the immune response to non-self antigens. Herein is an overview of our observations on the inhibition of the induction of splenic […]