sympathetic nervous system

Autonomic Nervous System Shift Linked to Infections following Acute Intracerebral Hemorrhage

Autonomic Nervous System Shift Linked to Infections following Acute Intracerebral Hemorrhage

A report in the journal Stroke indicates that a sympathetic nervous system over-activity and predominance is associated with higher rate of infection following acute intracerebral hemorrhage (ICH). Stroke is a major cause of morbidity and the third leading cause of death in the Western world. Infections occur commonly following stroke and adversely influence outcome. Pulmonary […]

Aging and Alterated Sympathetic Innervation of Lymphoid Organs in Rodents: Implications

Aging and Alterated Sympathetic Innervation of Lymphoid Organs in Rodents: Implications

A study in Journal of Neuroimmunology suggests that aging is linked to significant alterations in the sympathetic nervous innervation of lymphoid organs that may contribute to aging-related immunosuppression, The sympathetic nervous system (SNS) is a major branch of the autonomic nervous system and the peripheral stress system. The function of the human SNS is altered […]

Dysfunctional Sympathetic-Immune Interface in Disease States of the Gastrointestinal Tract

Dysfunctional Sympathetic-Immune Interface in Disease States of the Gastrointestinal Tract

Overview article The sympathetic nervous system (SNS) is an integrative interface between the central nervous system and viscera that contributes to the maintenance of homeostasis. It is comprised of cholinergic preganglionic sympathetic neurons which innervate postganglionic sympathetic neurons (PGSNs) and adrenal chromaffin cells (ACCs). Catecholamines and sympathetic co-transmitters, including adenosine triphosphate (ATP), or a related […]

The Sympathetic Nervous System as a Regulator of Breast Cancer Metastasis

The Sympathetic Nervous System as a Regulator of Breast Cancer Metastasis

A study published in the journal Cancer Research identifies sympathetic nervous system (SNS) activation as a novel physiologic regulator of breast cancer metastasis to distant tissue sites. The effects of the neuroendocrine system and microenvironment on breast cancer metastasis remain largely unexplored. Sympathetic nervous system nerve fibers are present in organs that serve as key […]

Hypothalamic-Pituitary-Adrenal Axis Function in Rheumatoid Arthritis

Hypothalamic-Pituitary-Adrenal Axis Function in Rheumatoid Arthritis

Overview article The neuroendocrine and the immune system are important homeostatic mechanisms maintaining the integrity of the organism. The efficacy of these homeostats in dynamic internal and external environments is a basis for successful adaptation to endogenous and exogenous stimuli that the organism constantly encounters. The adaptive reactions are complex and their ‘self-protecting’ nature serves […]

The Discovery of Adrenaline

The Discovery of Adrenaline

Historical Perspectives The first practical discovery of adrenaline by man occurred when one of our ancestral hominids while out for a stroll was unexpectedly surprised by a sabre-toothed tiger. Isolating and naming the compound were not uppermost in our man’s mind at the time and it was not until the late nineteenth century that progress […]

Page 2 of 212