sympathetic nerve

Evidence for Small Fiber Neuropathy in the Cornea of Fibromyalgia Patients

Evidence for Small Fiber Neuropathy in the Cornea of Fibromyalgia Patients

A new study published in Seminars in Arthritis & Rheumatism indicates that in patients with fibromyalgia the density of small nerve fibers in the cornea is reduced, supporting an evolving concept that fibromyalgia is a small fiber neuropathy. Fibromyalgia is also considered a stress-related syndrome that affects predominantly women. Recent research suggests that fibromyalgia is […]

Vitamin D Deficiency May Contribute to the Reduction of Sympathetic and Sensory Innervation in Arthritis

Vitamin D Deficiency May Contribute to the Reduction of Sympathetic and Sensory Innervation in Arthritis

A new study published in Neuroscience demonstrates that vitamin D deficiency in experimental animals is related to sensory and sympathetic denervation and reduced neurotrophin levels in the synovium. Several studies have associated vitamin D levels with rheumatoid arthritis (RA) development in humans. Thus, low vitamin D levels are documented in patients with active RA. Also […]

Vagus Nerve Stimulation Ameliorates Disease Activity in a Rodent Model of Rheumatoid Arthritis

Vagus Nerve Stimulation Ameliorates Disease Activity in a Rodent Model of Rheumatoid Arthritis

A study published in PLoS ONE is perhaps the first to demonstrate that electrical neurostimulation of the vagus nerve reduces signs of inflammation and disease severity in the collagen-induced arthritis (CIA), a disease model of rheumatoid arthritis in rodents. Previous research indicates that cholinergic signaling along the vagus nerve is able to affect the production […]