stress and inflammation

Neurocognitive Pathways and Social Rejection-Induced Inflammatory Responses

Neurocognitive Pathways and Social Rejection-Induced Inflammatory Responses

A recent study published in the Proceedings of the National Academy of Sciences of the USA (PNAS) indicates that a social stressor involving social-evaluative threat and rejection elicits significant increases in inflammatory activity, as indexed by both soluble receptor for tumor necrosis factor-alpha (sTNFalphaRII) and interleukin (IL)-6. Recent evidence indicates that psychological stress may affect […]

Psychological Stress, Immunoregulatory Balance and Human Inflammatory Diseases

Psychological Stress, Immunoregulatory Balance and Human Inflammatory Diseases

A recent review published in the journal Immunology and Allergy Clinics of North America provides a brief but comprehensive overview of the major immune mechanisms affected by stress, and the relationships linking stress with various inflammatory diseases. In this review, Gailen Marshall from the University of Mississippi Medical Center outlines recent data indicating that immunoregulatory […]

Robert Sapolsky and Why Zebras Don’t get Ulcers

Robert Sapolsky and Why Zebras Don’t get Ulcers

SHORT FEATURES and FACES ARTICLE Robert Sapolsky, a neuroendocrinologist and John A. and Cynthia Fry Gunn Professor at Stanford University, has focused his research on issues of stress and neuronal degeneration, as well as on the possibilities of gene therapy strategies for protecting susceptible neurons from disease. In his Science article, entitled ‘Why Stress Is […]

Pro- and Anti-Inflammatory Effects of Stress in the Brain: Mechanisms and Implications

Pro- and Anti-Inflammatory Effects of Stress in the Brain: Mechanisms and Implications

Overview Article Some stress protocols show a pro-inflammatory response in the brain and other systems characterized by a complex release of several inflammatory mediators such as cytokines, transcription factors, prostanoids and free radicals. Such response might contribute to cell damage during several neuropsychiatric diseases related with stress (post-traumatic stress disorder, major depressive disorder, anxiety disorders, […]

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