First Evidence that the Antiviral Remdesivir Shows Efficacy in an Animal Model (Rhesus Macaques) of COVID-19
As reported by Brandi Williamson et al. in bioRxiv, remdesivir is the first antiviral treatment with proven efficacy against SARS-CoV-2 in an animal model of COVID-19. This study involving four laboratories from the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH) and the Gilead Sciences, Foster City, CA, USA, indicates […]
Commentary Note that the information contained herein is NOT instructional for medical diagnosis or treatment, see the BrainImmune DISCLAIMER at the end of this article! The pandemic viral illness COVID-19 is especially life-threatening in the elderly and in people with any of a variety of underlying medical conditions. No conceptual framework has been offered as […]
β2-Adrenoceptor-Mediated Upregulation of IL-17 May Contribute to Pulmonary Immunopathology in COVID-19: Does Blockade of IL-17 and β-Adrenergic Effects Hold a Therapeutic Potential?
Research Hypothesis Note that this is a research hypothesis – the information contained herein is NOT instructional for medical diagnosis or treatment, see the BrainImmune DISCLAIMER at the end of this article! It has been reported that nucleotide-binding oligomerization domain 2 (NOD2) can also function as a cytoplasmic viral pattern recognition receptor (PRR) by triggering […]