prostate cancer

Autonomic Nerves May Contribute to Prostate Cancer Development

Autonomic Nerves May Contribute to Prostate Cancer Development

In the July 2013 issue of Science magazine, Claire Magnon et al. provide evidence that autonomic nerves contribute to prostate cancer development, where the sympathetic nervous system (SNS) via the activation of β2 and β3-adrenergic receptor pathway participate in the early phase of tumor development. On the other hand, the parasympathetic (cholinergic) nervous system plays […]

Stress promotes tumor growth by amplifying the cancer cells’ ability to evade apoptosis

Stress promotes tumor growth by amplifying the cancer cells’ ability to evade apoptosis

A study published in the Journal of Clinical Investigation indicates that stress or the stress hormone adrenaline, through stimulation of beta-adrenoreceptors (ADRs), activate signaling pathways that lead to the inhibition of apoptosis. This enables prostate cancer cells to evade apoptosis, which is an important feature of tumor growth and metastasis. An increasing body of evidence […]

Biobehavioral Factors, Stress and Cancer Progression: A Contemporary Review

Biobehavioral Factors, Stress and Cancer Progression: A Contemporary Review

In two recent reviews, published in 2011, Erin Costanzo, Anil Sood and Susan Lutgendorf provide a contemporary overview of the major pathways involved in the cross-talk between behavioral factors and the immune system that contribute to cancer development  and progression. The idea that psychological factors may contribute to cancer development and progression is not new. […]

Celebrities, Stress and Cancer

Celebrities, Stress and Cancer

SHORT FEATURES and FACES ARTICLE Recently, several websites have reported that Michael Douglas has been diagnosed with throat cancer. The actor believes a combination of his previous hard-driving lifestyle and the stresses of the past 12 months may have caused the cancer. He tells UK’s Daily Mirror that stress was a major factor: “This type […]