ovarian cancer

Beta Adrenoreceptor – Src Kinase Signaling As a Trigger for Cancer Metastasis

Beta Adrenoreceptor – Src Kinase Signaling As a Trigger for Cancer Metastasis

In the July 2013 issue of Nature Communications, Armaiz-Pena et al. demonstrate that stress is able through activation of beta-adrenergic signaling in tumor cells to trigger a critical phosphorylation event, resulting in Src kinase activation, which in turn, can affect tumor growth and metastasis. Building on previous work showing that sympathetic nervous system activity can […]

Beta Blockers Improve Survival in Ovarian Cancer Patients

Beta Blockers Improve Survival in Ovarian Cancer Patients

At a recent meeting of the American Society of Gynecologic Oncology in Los Angeles, CA., Anil Sood, MD, and colleagues from the MD Anderson Cancer Center in Houston, reported that patients with advanced ovarian cancer had significantly better survival if they took beta blockers. In the past few years, more than a dozen studies have […]

Biobehavioral Factors, Stress and Cancer Progression: A Contemporary Review

Biobehavioral Factors, Stress and Cancer Progression: A Contemporary Review

In two recent reviews, published in 2011, Erin Costanzo, Anil Sood and Susan Lutgendorf provide a contemporary overview of the major pathways involved in the cross-talk between behavioral factors and the immune system that contribute to cancer development  and progression. The idea that psychological factors may contribute to cancer development and progression is not new. […]