neuroimmunology

The Neuroimmunological Basis of Behavior and Mental Disorders

The Neuroimmunological Basis of Behavior and Mental Disorders is published by Springer and edited by Allan Siegel, Ph.D. and Steven S. Zalcman, Ph.D. Neurosciences and immunology developed independently for many years, and thus, the question of how the brain communicates with the immune system remained enigmatic until fairly recently. The immune system has been regarded […]

The Immune System and the Developing Brain

The Immune System and the Developing Brain (Colloquium Series on the Developing Brain) is published by Morgan & Claypool Life Sciences and authored by Jaclyn M. Schwarz, from the Department of Psychological and Brain Sciences, University of Delaware and Staci D. Bilbo, the Director of Research for the Lurie Center for Autism at of Massachusetts […]

Disruption of Brain TNF Homeostasis Elicits Maladaptive Alterations Producing Chronic Pain

Disruption of Brain TNF Homeostasis Elicits Maladaptive Alterations Producing Chronic Pain

Overview article We have determined that enhanced expression of the pro-inflammatory cytokine Tumor Necrosis Factor (TNF)-α by both neurons and glial cells of the brain direct the process involved with the development and also the maintenance of neuropathic pain. However, TNF is not only a pro-inflammatory cytokine but is also a potent neuromodulator. TNF specially […]

Th17 and Th22 Cells May Contribute To the Pathogenesis of Guillain-Barré Syndrome

Th17 and Th22 Cells May Contribute To the Pathogenesis of Guillain-Barré Syndrome

A study by Shujuan Li and colleagues from the Jilin University, Changchun, China, suggests that Th17 and Th22 cells might be involved in the onset and development of Guillain-Barré Syndrome. Guillain-Barré syndrome (GBS), described in 1916 by George Guillain, Jean-Alexandre Barré, and André Strohl, is an acute inflammatory immune-mediated polyradiculoneuropathy presenting typically with tingling, progressive […]