Antibiotics through Effects on the Microbiota-Gut-Brain Axis and Inflammatory Monocytes May Reshape Brain Hippocampal Neurogenesis
A new Cell Reports study indicates that ‘inflammatory’ monocytes may represent the missing ‘pathogenic link’ between the antibiotics’ effects on gut microbiota, and the subsequent changes in the brain hippocampal neurogenesis and plasticity. Recent research suggests that antibiotics may exert some of their unsolicited side effects through effects on the gut-brain axis. Soon after birth, […]
Parkinson’s Disease: Peripheral Immunity Links Neurodegeneration and the Intestinal Microbiota
Posted on August 24, 2019 By Marco Cosentino Commentaries
Commentary By Marco Cosentino, Cristoforo Comi and Franca Marino On the study by Matheoud D et al., Nature, 2019; 571(7766):565-569; Doi: 10.1038/s41586-019-1405-y, Intestinal infection triggers Parkinson’s disease-like symptoms in Pink1-/- mice. Parkinson’s disease (PD) is a chronic neurodegenerative disease affecting 7 to 10 million people worldwide, 1% above 60 years of age and up to […]