immune system and nervous system

Experimental Study Shows that Learned Immunosuppressive Placebo Responses Attenuate Disease Progression in a Rat Model of Arthritis

Experimental Study Shows that Learned Immunosuppressive Placebo Responses Attenuate Disease Progression in a Rat Model of Arthritis

A recent study published in Arthritis & Rheumatology showed that inflammatory symptoms in experimentally induced arthritis in rats are attenuated by using learned immunosuppressive placebo responses. Therapy of chronic inflammatory autoimmune diseases such as rheumatoid arthritis requires long lasting if not continuous treatment with immunosuppressive drugs. However, therapy with most small-molecule immunosuppressive drugs commonly induces unwanted […]

Sympathetic Nervous System Dysfunction in Rheumatoid Arthritis: Brief Overview

Sympathetic Nervous System Dysfunction in Rheumatoid Arthritis: Brief Overview

Rheumatoid arthritis (RA) is an autoimmune condition characterized by chronic inflammation occurring locally within the synovial joints and systemically. Accumulating evidence supports an important role of the sympathetic nervous system in the pathophysiology of RA, both as a cause and consequence of inflammation. Acute sympathetic activation results in a shift from a T-helper (Th) 1 […]

Bridging Neurosciences and Immunology – An Overview

Bridging Neurosciences and Immunology – An Overview

Historical Perspectives The brain and the immune system, or the “supersystems”, a term coined by Tomio Tada (1997), are the two major adaptive systems of the body. Although the immune system has been often regarded as autonomous, the evidence accumulated over several decades indicates that the central nervous system (CNS) receives messages from the immune […]