fibromyalgia

The Chemokines CX3CL1 and IL-8 May Be Implicated in the Pathogenesis of Fibromyalgia

The Chemokines CX3CL1 and IL-8 May Be Implicated in the Pathogenesis of Fibromyalgia

A new study published in the Journal of Pain Research reports the presence of high levels of the chemokines CX3CL1 (also known as fractalkine) and interleukin-8 (IL-8) in fibromyalgia (FM) patients. Fibromyalgia is the “current term for chronic widespread musculoskeletal pain for which no alternative cause can be identified”. Typical symptoms includes chronic widespread pain, […]

An Association between Widespread Pain and Serum IL-8 Levels in Fibromyalgia Patients

An Association between Widespread Pain and Serum IL-8 Levels in Fibromyalgia Patients

Ozdolap S, et al. recently reported, at the European League against Rheumatism Annual European Congress of Rheumatology, June 10-13, 2015, a positive correlation between widespread pain and serum IL-8 in patients with fibromyalgia (FM). This substantiates previous work indicating that the pro-inflammatory chemokine IL-8 may contribute to the pathogenesis of fibromyalgia (Wang H. et al., […]

Sympathetic Dysautonomia in Fibromyalgia: Brief Overview

Sympathetic Dysautonomia in Fibromyalgia: Brief Overview

Evolving Concepts Fibromyalgia (FM) is a stress-related disorder that predominately affects women. FM’s outstanding clinical features are chronic widespread pain, paresthesias, allodynia, fatigue, sleep difficulties and cognitive impairment. Other FM associated symptoms relate to irritable bowel, temporo-mandibular dysfunction and interstitial cystitis [1]. FM pathogenesis has not been elucidated. Our group has proposed dysautonomia as an […]

Evidence for Small Fiber Neuropathy in the Cornea of Fibromyalgia Patients

Evidence for Small Fiber Neuropathy in the Cornea of Fibromyalgia Patients

A new study published in Seminars in Arthritis & Rheumatism indicates that in patients with fibromyalgia the density of small nerve fibers in the cornea is reduced, supporting an evolving concept that fibromyalgia is a small fiber neuropathy. Fibromyalgia is also considered a stress-related syndrome that affects predominantly women. Recent research suggests that fibromyalgia is […]

“You just do it.”

“You just do it.”

Great quote for people living with fibromyalgia. “Damn! Elizabeth Taylor hit it right on the head…I’m sure she wasn’t talking about fibromyalgia, but this IS everyone’s life at some point. Some of us just face it more often than others”. From BrainImmune on Pinterest, via Kelly Roth Fibromyalgia, is a stress-related disorder that affects approximately […]

First Report That Interleukin-17A Levels Are Increased In Fibromyalgia Patients

First Report That Interleukin-17A Levels Are Increased In Fibromyalgia Patients

A recent study by Andrei Pernambuco and colleagues from the Federal University of Minas Gerais, Belo Horizonte, MG, Brazil is perhaps the first to document increased plas­ma levels of interleukin (IL)-17A in fibromyalgia (FM) patients. Interleukin-17 and the T helper (Th)-17 cells play a key role in tissue inflammation and host defense and, recently, the […]