cortisol receptor

Important New Features and Glucocorticoid-Resistance of Pro-Inflammatory Th17 Cells

Important New Features and Glucocorticoid-Resistance of Pro-Inflammatory Th17 Cells

A recent study by Radha Ramesh and colleagues, published in the Journal of Experimental Medicine indicates that the expression of the multi-drug transporter MDR1 (also known as P-glycoprotein [P-gp] and ABCB1) is a marker that defines the pro-inflammatory nature of T helper (Th)17 cells. The Th17 cells are major players in inflammatory/autoimmune conditions, but not […]