cardiovascular disease

Inflammation Causing Hypertension: A New Concept Reviewed

Inflammation Causing Hypertension: A New Concept Reviewed

In a recent review article David Harrison and colleagues from the Department of Medicine, Vanderbilt University, Nashville, TN, summarize recent animal and human studies suggesting that inflammation and adaptive immunity responses are implicated in the pathogenesis of hypertension. As stated by the authors, quote: “A prominent pathology textbook used in the United States includes an […]

Elevated Plasma IL-10 Levels are a Strong Predictor of Long-Term Adverse Outcomes in Acute Coronary Syndrome

Elevated Plasma IL-10 Levels are a Strong Predictor of Long-Term Adverse Outcomes in Acute Coronary Syndrome

Interleukin (IL)-10 is often considered as a ‘cardioprotective’ cytokine, but a recent study published in the American Journal of Medicine reports an ‘unexpected’ observation that elevated baseline plasma levels of IL-10 are a strong predictor of long-term adverse cardiovascular outcomes in patients with acute coronary syndrome. Interleukin-10 is an immunoregulatory cytokine with strong anti-inflammatory properties. […]

Stress, Immunity and Coronary Artery Disease

Stress, Immunity and Coronary Artery Disease

In this review Roger Ho and colleagues discuss how stress hormones through affecting different components of the immune/inflammatory reaction may in turn contribute to the development of coronary artery disease (CAD). Recent evidence indicates that acute and chronic psychological stress, such as intense anger, low socioeconomic status, work stress, social isolation, depression, anxiety and hostility […]

Childhood Roots of Health Disparities

Childhood Roots of Health Disparities

Recently, in the Journal of the American Medical Association (JAMA), Jack Shonkoff, W. Thomas Boyce and Bruce McEwen discussed a new way of thinking about health promotion and disease prevention. Adult conditions such as coronary heart disease, stroke, diabetes, and cancer are believed to be causally related to adult behavior and lifestyles only. But recent […]

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