cardiovascular disease

Psychosocial Stress and Cardiovascular Disease in Women: Concepts, Findings, Future Perspectives

Psychosocial Stress and Cardiovascular Disease in Women is edited by Kristina Orth-Gomér, Neil Schneiderman, Viola Vaccarino and Hans-Christian Deter, and published by Springer. Not long ago, it was assumed that coronary heart disease mainly–or only–affected men. Now that CHD is recognized as a leading killer of women as well as men, numerous research studies have […]

Stress and Cardiovascular Disease

Stress and Cardiovascular Disease is edited by Paul Hjemdahl, Annika Rosengren and Andrew Steptoe and published by Springer. An increasing body of evidence indicates that psychological stress and cardiovascular diseases are intertwined more closely than initially suspected about 4-5 decades ago. In fact, many clinical and epidemiological studies have documented the link between psychological stress […]

Psychological Factors and Cardiovascular Disorders: The Role of Stress and Psychosocial Influences

Psychological Factors and Cardiovascular Disorders is edited by Leo Sher, and published by Nova Kroshka Books. Psychological factors significantly affect the cardiovascular system and play an important role in the etiopathogenesis of cardiovascular disorders. In fact, psychological stress in childhood, adulthood or persistent across a person’s life can contribute to high cardiovascular and metabolic risk. […]

First Evidence that IL-9 Contributes to Atherosclerosis Development

First Evidence that IL-9 Contributes to Atherosclerosis Development

Perhaps the first evidence for an involvement of IL-9 in atherosclerosis was recently reported in the online journal PLoS One by Ida Gregersen and colleagues from the Oslo University Hospital Rikshospitalet, Oslo, Norway. Interleukin (IL)-9 is a cytokine linked mostly to T helper (Th)2 cell responses and Th2-related conditions such as parasitic helminth infections and […]

Colchicine May Prove Useful In the Treatment of Acute Coronary Syndrome

Colchicine May Prove Useful In the Treatment of Acute Coronary Syndrome

A study by Gonzalo Martınez et al., published in the Journal of the American Heart Association indicates that colchicine may also be useful for the treatment of heart attacks by reducing cardiac inflammation and the local pro-inflammatory cytokine production. Colchicine is an alkaloid with potent anti-inflammatory effects, which is often used for the treatment of […]

Evidence that Napping May Correct Interleukin-6 Changes and the Stress Induction Caused By Sleep Deprivation

Evidence that Napping May Correct Interleukin-6 Changes and the Stress Induction Caused By Sleep Deprivation

A study published in the March issue of The Journal of Clinical Endocrinology & Metabolism (JCEM) indicates that short-term napping is able to restore, to a great extent, the neurohormonal and immune changes induced by sleep deprivation. Insufficient sleep is well-known to be associated with poor attention and performance deficits. However, an increasing body of […]

Short Breastfeeding Duration and Low Birth Weight Linked To High Adulthood CRP Levels: Implications for Cardiovascular Disease Risk

Short Breastfeeding Duration and Low Birth Weight Linked To High Adulthood CRP Levels: Implications for Cardiovascular Disease Risk

A recent study by Thomas McDade and colleagues from the Northwestern University, IL, USA, suggests that lower birth weight babies breastfed less than three months, or not at all, are more likely as young adults to have higher levels of chronic inflammation. Systemic inflammation plays a major pathogenic role in cardiovascular (CV) diseases, insulin resistance, […]

The Emerging Role of Innate Immune Cells’ Network and the Cardio-Splenic Axis in Heart Failure

The Emerging Role of Innate Immune Cells’ Network and the Cardio-Splenic Axis in Heart Failure

A new study published in the journal Circulation Research is perhaps the first to show changes of the innate cells network and traffic in ischemic heart failure. Heart failure (HF) remains a major health issue, and evidence accumulated over the last decade has established immune activation or inflammation as a major pathogenic factor in chronic […]

Interleukin-6 – a Better Predictor of Future Cardiovascular Events Than C-Reactive Protein?

Interleukin-6 – a Better Predictor of Future Cardiovascular Events Than C-Reactive Protein?

In a study published in the journal Cytokine, Hidenori Nishida and colleagues from the National Cerebral and Cardiovascular Center, Suita, Japan, demonstrate that an increased level of serum IL-6 is a significant predictor of future cardiovascular (CV) events in high-risk Japanese patients, independently of a variety of influencing factors. One of the paradigm shifts in […]

Negative and Competitive Interpersonal Stressors Linked to High Proinflammatory Cytokine Responses

Negative and Competitive Interpersonal Stressors Linked to High Proinflammatory Cytokine Responses

In a recent PNAS study, Jessica Chiang and colleagues from the Department of Psychology, David Geffen School of Medicine, University of California, Los Angeles, investigated the potential importance of negative, competitive and positive daily interactions on inflammatory activity. The authors of this study demonstrate that negative social interactions significantly predicted higher baseline levels of sTNFaRII […]

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