Ashley Winning et al. from the Harvard T.H. Chan School of Public Health, Boston, Massachusetts report in the the Journal of the the American College of Cardiology that psychological stress in childhood, adulthood or persistent across a person’s life can contribute to high cardiovascular and metabolic risk.
The Ashley Winning et al. study published in the Journal of the the American College of Cardiology is based on longitudinal data from the 1958 British Birth Cohort Study.
This report is perhaps the first to suggest that “increased risk of cardiometabolic disease associated with distress in childhood may be maintained even if distress remits by adulthood”.
As per the mechanisms behind these relationships, the authors suggest that they may reflect effects of the hypothalamic-pituitary-adrenal axis and sympathetic nervous system on processes related to cardiometabolic and immune functioning, blood pressure and lipid metabolism.
They also propose that psychological stress across the lifespan should be considered during cardiovascular risk assessment.
Source: J Am Coll Cardiol, 2015, 66:1577. doi: 10.1016/j.jacc.2015.08.021. Read More: J Am Coll Cardiol