Stress, Immune Function, and Health: The Connection

Stress Immune Function Health Bruce Rabin book amazonThe ‘Stress, Immune Function, and Health: The Connection’ is written by Bruce S. Rabin, MD, PhD, a renowned physician-scientist and clinical immunologist. Dr. Rabin is professor of pathology and the director of the Division of Clinical Immunopathology, Department of Pathology at the University of Pittsburgh School of Medicine, US.

Stress, Immune Function, and Health: The Connection is a single-author book, where Dr. Rabin provides his perspectives on brain- and stress-immune interactions, and how the activation of the central nervous system by stressful challenges influence the function of the immune system. The book represents an authoritative guide for physicians, scientists and for students in the fields of immunology, neuroscience and physiology.

The books provides an overview of the immune and nervous systems’ function and how these two major adaptive system are involved in functionally relevant cross-talk. In support of that interaction, research using animal models of stress has provided valuable information as to the effect of stress on basic immune function and susceptibility to infectious disease.

The books addresses issues such as stress and immunity, and different hormonal mechanisms of the central nervous system-immune system interactions. This includes the effects of the hypothalamic pituitary adrenal (HPA) axis and the peripheral autonomic nervous system, including the sympathetic nervous system. The author Bruce Rabin also demonstrates, in a concise, accessible manner, the ability of an individual’s immune system to alter susceptibility to immune-mediated diseases.

The book also deals with several key issues in this rapidly expanding field, including:

  • How distinct areas of the brain perceiving stressors challenges are able to communicate with the immune cells.
  • Psychological stress and stress-induced risks of disease development.
  • The effect on the immune system due to stress from an increased levels of different neurotransmitters, neuropeptides and hormones.
  • The issue of stress during pregnancy and its short and long-term effects.

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