The Physiology of Immunity

he Physiology of ImmunityThe Physiology of Immunity (Comparative Immunology) provides an overview of the immune system and integrates physiology and immunology, outlining the effects of the neuroendocrine system on immunity, and comparing the neuroendocrine-immune function of a variety of species.

Neuroendocrine-immunology or immunophysiology has become a highly visible and fast-growing area in modern inter-disciplinary research. This book’s sections focus on the neuroendocrine regulation of the immune system in conditions such as reproduction, pregnancy, stress and aging.

The text is organized in seven sections, beginning with an introduction to the immune system. Section II outlines how the central nervous system (CNS) communicates with central and peripheral lymphoid organs. Section III provides information on factors from the immune system that act as messengers to the CNS. The metabolic regulation of growth and development is discussed in Section IV. Section V examines the interactions occurring between the reproductive and immune systems.

The effects of other physiologic stressors on immunity are reviewed in Section VI. Section VII considers cyclic and periodic influences on the immune system. Finally, there is a consideration of a new unifying theory for immunology.

Selected chapters are highlighted below:

  • Neuropeptides and the Immune System
  • Mediators of CNS Activity-Neuroendocrine-Immune (NEI) Interactions
  • Peripheral and Central Neural Mechanisms for Immune Regulation through the Innervation of Immune Effector Sites
  • The Role of Calcitonin Gene-Related Peptide (CGRP) and Other Sensory Neuropeptides in Modulating Inflammation and Immunity
  • CNS Biogenic Amines and the Immune System,
  • The Neuroendocrine Activity of the Thymus
  • Effects of Growth Hormone, Insulin-Like Growth Factor-I (IGF-I) and Somatostatin on Immune Function and Development
  • Interactions between the Thyroid and the Immune System
  • Estrogen-Mediated Interactions between the Immune and Female Reproductive Systems
  • The Role of Androgens-Androgen Receptor on Immune System Activity
  • Unique Neuroendocrine-Immune Interactions during Pregnancy
  • Stress and Neuroendocrine-Immune Interactions
  • The Hypothalamic-Pituitary-Adrenocortical Immune Axis
  • Circadian Rhythms and Immunity: T-Helper-2 Cells as Targets of the Circadian Melatonin Signal
  • Aging and Immunity

Hardcover: 464 pages; Publisher: CRC Press; 1 edition (September 30, 1996)

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