Neural-Immune Interactions in Brain Function and Alcohol Related Disorders

Neural-Immune Interactions Alcohol Related DisordersNeural-Immune Interactions in Brain Function and Alcohol Related Disorders presents the recent advances in neuro-immune and alcohol research, relevant to brain function, behavior and alcohol use disorders.  Recent up-to-date and cutting edge development is provided by experts in the field of neuroendocrine-immunology and alcohol use disorders.

Neuroendocrine-immunology and neural-immune interactions offer a new framework for understanding neurodevelopment and a variety of neurological disorders. The progress in this relatively new interdisciplinary field has a far reaching impact on many areas of neuroscience, including alcohol research. Studies using human alcoholic brains, gene knockout mice, and gene expression profiling have established a clear link between alcoholism and altered neuroimmune profiles.

Neural–Immune Interaction in Brain Function and Alcohol Related Disorders focuses on neural-immune interactions in areas directly related to alcohol use disorders. However, research topics such as sleep disorders, pain, and cholinergic anti-inflammatory pathways are not covered as independent chapters but briefly mentioned in the text. The close relevance of these topics to neural-immune interactions and alcohol use disorders warrants future discussion and more research efforts.

Few selected chapters are listed below:

  • Neuroimmune Modulation of Synaptic Function
  • Neuroimaging and Clinical Studies on Brain–Immune Interactions
  • Mechanisms of Stress-Dependent Neuroinflammation and Their Implications for Understanding Consequences of Alcohol Exposure
  • Neuroimmune Cross Talk and HIV-Associated Neurocognitive Disorders
  • Innate Immune Signaling and Alcoholism
  • Role of Toll-Like Receptor 4 in Alcohol-Induced Neuroinflammation and Behavioral Dysfunctions
  • Prenatal Alcohol Exposure: Impact on Neuroendocrine–Neuroimmune Networks
  • Neuroimmune Mechanisms of Glia and Their Interplay with Alcohol Exposure Across the Lifespan
  • Effects of Morphine and Alcohol on the Hypothalamic–Pituitary–Adrenal Axis, Immunity, and Cognitive Behavior
  • Therapeutic Strategies to Treat Alcohol-Related Disorders Targeting Central Immune Signaling
  • Alcohol and the Neuroimmune Response: Current Status and Future Directions

Hardcover: 588 pages; Publisher: Springer; 2013 edition (October 25, 2012)

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