BrainImmune

ADVANCING NEUROENDOCRINE–IMMUNOLOGY RESEARCH

 

 

 

 

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Prenatal Immune Challenge May Act As A ‘Disease Primer’ Increasing the Offspring’s Vulnerability to the Neuro-Pathological Effects of Stress in Puberty

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Epidemiologic studies indicate that prenatal infection may play an important role in the etiopathogenesis of schizophrenia, which is primarily a neurodevelopmental disorder.

Beta Blockers Improve Survival in Ovarian Cancer Patients

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In the past few years, more than a dozen studies have suggested that beta blockers hold substantial potential for therapeutical interventions in cancer.

Stress promotes tumor growth by amplifying the cancer cells’ ability to evade apoptosis – evidence from two animal models of prostate cancer

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An increasing body of evidence indicates that psychological stress, i.e., stress hormones and mediators, are involved in the development and progression of cancer – affecting directly or indirectly tumor growth, angiogenesis, and migration or invasion of tumor cells.

The Interplay between Neuropeptide Y, Neuropeptide Y2 Receptors and Pro-Inflammatory Cytokines May Contribute To Atherosclerotic Plaque Instability

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Increasing body of evidence indicates that both inflammation and psychological stress contribute to the development of atherosclerosis.

Neurotensin and CRH Work Together To Induce Mast Cell Activation: Implications for Stress-Induced Exacerbations of Allergic and Autoimmune/Inflammatory Diseases

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Psychological stress is known to aggravate asthma, migraines and certain autoimmune/inflammatory diseases.

An Enterovirus Attacking the Thymus, the Safeguard Organ against Autoimmunity, May Play a Key Role in Triggering Type 1 Diabetes

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While an increasing number of studies, mainly epidemiological, indicate that coxsackie viruses (CVs) play a role in the pathogenesis of autoimmune type 1 diabetes (T1D), the mechanisms of action of these viruses remain elusive.

Expression of Neurotensin and Its Receptors in B Cells: Implications for Chronic B Cell Lymphocytic Leukemia

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Neurotensin is a 13-amino acid peptide discovered and isolated in 1973, from extracts of bovine hypothalamus by Robert Carraway and Susan Leeman.

Maternal Stress, Neuropeptide Y – NPY-Y2R System and Programming for the Offspring’s Vulnerability to Obesity and Metabolic Syndrome

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According to CDC more than one-third of U.S. adults (35.7%) are obese.

Psychological Distress Is Dose-Dependently Related to Increased Mortality

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Psychological stress has been linked to the development and progression of several common human diseases including allergy, cancer, cardiovascular and autoimmune disorders (see Clinical Aspects, News and Features and Faces sections, and Evolving Concepts category of this website).