BrainImmune publishes short but comprehensive online chapters that cover the broad spectrum of fundamental and clinical aspects of the neuroendocrine-immune interactions and their impact on health and disease. BrainImmune provides state of the art information, and new ideas and conceptual frameworks in this vast inter-disciplinary area. The BrainImmune chapters are written by experts in the field whose research has had a major influence on the development of the topic reviewed.
Our major target audience is biomedical researchers, physician-scientists, practicing physicians, health care providers, students and trainees. We expect to generate quite a substantial interest from the lay public.
We would like to keep a very liberal style – but keep in mind some important aspects:
1. This is online, internet publishing. When it comes to a quick reference or concise opinions, the first place that life scientists and physicians turn to is the internet. Thus, keep the style clear, concise and to the point. The style and format should be close to short review or overview, or short but comprehensive book chapter.
2. We cover a very broad spectrum and interface from neurosciences, endocrinology, psychiatry, psychology and psychosomatics to immunology and molecular biology. Keep in mind that this is online publication, and a substantial part of readers are not experts in your field. It is instrumental to give enough background and the text should be intelligible to non-specialists, with definitions of unfamiliar technical terms and explanations of difficult or controversial points included. At the same time, the overview is to be sufficiently precise and detailed to command the attention and respect of experts in the field.
3. Authors are asked to be critical of methods, results, and conclusions and to challenge accepted concepts where warranted. Conflicting points of view are to be presented objectively in good perspective.
4. Use American English spelling and minimize the use of nonstandard abbreviations.
The usual length corresponds to about 15 to 40 double-spaced typewritten manuscript pages in Word format. In addition, diagrams, tables, and illustrations should be included to bring out new concepts and important relationships.
History chapters are, by definition, much shorter and their length corresponds to about 5 to 15 double-spaced typewritten manuscript pages in Word format.
1. General Guidelines and Formats
Submission of a manuscript amounts to assurance that it has not been copyrighted, published, or accepted for publication elsewhere, that it is not currently being considered for publication elsewhere, and that it will not be submitted elsewhere while under consideration by BrainImmune.
a) The manuscript should be submitted as a Microsoft Word (DOC) file. In the file''s name please include your family name and the brief name of section''s title. For review purposes only, please submit the complete manuscript, including tables and figures as a single PDF file.
b) Manuscripts must be paginated and double-spaced throughout. Separate paragraphs by a space, but do not indent.
c) For uniformity, we suggest using Arial font, 11 point, throughout the entire manuscript with main titles/headings and authors/affiliations in Arial, 12 point, bold. For Greek characters you must use the insert symbol function from Word.
d) Use italics for: scientific names of bacteria and protozoa; genera, species, and subspecific taxa; chemical names, i.e. p, o, m, n, cis, sec, sic, trans, syn; genes, genotypes, loci, markers, mutants, alleles, operons; mathematical variables; strictly defined introduced terms.
e) Do not use italics for: emphasis; common foreign words such as ad hoc, a priori, in vivo, in vitro; abbreviations such as sp., spp., var.; names of taxa of ranks higher than genus; generic names used as adjectives; names of microorganisms used colloquially (e.g., actinomycetes); strain designations; names of cells, phages, hosts, phenotypes; R, X, M, B, A, etc. in formulas and equations where they represent chemical elements or groups.
2. Title Page
a) The full title.
b) Each author''s full name (first name, middle initial, last name) and the affiliations of all authors and their institutions, departments, or organizations (use the following symbols in this order to designate authors'' affiliations: *, †, ‡, §, , ||, #, **, ††, ‡‡, §§, , || ||, ##). Authors may also present their names in non-Latin characters (in their native writing system) along side the standard English transliteration of their name in the main author line; for example, "Ta-Ming Wang (王大明)". Use any non-Latin languages that have standard Unicode characters designated for the native characters. Please only provide the native expression for the original written form of the transliterated name; that is, do not include any associated degree, rank, or title information in the native format. This feature is meant for the person''s name only.
c) 7-to-10 key words.
d) List of nonstandard abbreviations used in the text.
e) Contact information of corresponding author: e-mail address, phone and fax number.
Abstracts are optional, when being submitted, abstracts must be 150 words or less, reference citations should not be included and the species of animals or species of origin of cells used in the manuscript must be clearly stated.
As mentioned above, this is an online publication, and a substantial part of readers are not experts in your field. Please give enough background and put the overview in historical context.
5. The rest of the text
It is the author''s choice how he/she will structure the chapter or overview. Provide clear-cut and simple headings and subheading that will be listed, together with abbreviations on the front page of your chapter.
You must provide conclusions with a short summary of the key concepts and ideas discussed. If appropriate, this section can also indicate areas of the field that need further attention and/or areas of future investigation. We strongly encourage, when appropriate, to provide the possible clinical implications of your results, ideas, concepts, etc. In this case, this section should be entitled as ''Conclusions and clinical implications''.
This section is placed at the end of the text and sources of financial support are cited. This information must be in the form of a sentence with the name of the funding agency written out in full.
We would like to make very liberal use of lists, tables and figures since these can provide quick and effective data for practicing physicians who may not have time to read lengthy text. Tables should be produced using the MSWord table function, since they will hold together best during email.
Tables should always use rows and columns to correlate two variables. Double space tables on pages separate from the text and make them self-contained and self-explanatory. Do not divide into sub tables and do not use vertical rules. Label each table at the top with a Roman numeral followed by the table title. Insert explanatory material and footnotes below the table. Designate footnotes using lowercase superscript letters (a, b, c) reading horizontally across the table. Supply units of measure at the heads of the columns. Abbreviations that are used only in a table should be defined in the footnotes to that table.
9. Figures and Illustrations
For the sake of the general readership, authors are especially encouraged to use "model" diagrams that illustrate hypothesized physiological mechanisms or key technical considerations. The author may wish to reproduce primary data if those data clearly illustrate an important physiological and/or technical principle. Figures will be included directly in the text. Provide figures and images in JPEG formats.
a) Figure Legends: Include a short title after the figure number. In addition, give a short explanation in sufficient detail to make the data intelligible without reference to the text (ideally figure legends should be no more than 150 words). Symbols used in the figure must be explained in the figure legend.
b) Permissions: As usual, we will need written permission to re-use any figure published elsewhere. Since many journals charge for permission to re-use a figure, and we are unable to provide support for this expense, it is often preferable to modify an illustration so that it is not the same as the original, or to produce a new figure, rather than republishing a figure. Often authors, if asked, will provide a new and different figure for your use and they can be given credit.
Letters of permission should accompany the manuscript in the following circumstances:
- for permission from the publisher and author to use previously published tables, illustrations, and quotations that exceed 100 words. Full credit for such material must be given in the figure or table caption, and should be cited exactly as specified by the copyright holder. When in doubt, request permission. Modified or adapted illustrations do not require permissions.
- for permission from any individual who is listed in a "personal communication" for reference material;
- for permission to discuss information that an individual has "in press."
10. Abbreviations, names, units, drugs, receptor nomenclature etc.
A short list of standard abbreviations is available at the end of the instructions for authors. Terms that do not appear in the list must be used three or more times in a manuscript to justify abbreviation. When using nonstandard abbreviations, the full term should be spelled out at the first mention, followed by the abbreviation in parentheses. The abbreviation should be used consistently thereafter. All nonstandard abbreviations should be listed in alphabetical order on the title page. The use of abbreviations should be minimized to enhance readability and comprehension of the text. Keep in mind that abbreviations that are familiar to neuroscientists may not be familiar to immunologists, and vice versa.
a) For biochemical abbreviations, use those currently recommended by The Journal of Biological Chemistry in its instructions to authors. Italicize genes and loci, and use approved names listed in the appropriate nomenclature database. Avoid using multiple names for genes and proteins; alternative names should be given on first mention only. For special materials and equipment, give the manufacturer''s name. Abbreviate units of measure only when used with numbers. Specify estimates of variance (e.g., SD, SE) and give references for statistical methods.
b) When reporting values for commonly studied components (α1-antitrypsin, ammonia, bilirubin, calcium, cholesterol, creatinine, etc.), report the value in SI units with traditional units given in parentheses.
c) Drugs: Generic drug names are used in text, tables and figures. Trade names may be given in parentheses following the first text reference, but should not appear in titles, figures, or tables. Whereas trade names are capitalized, generic or chemical names are not. The chemical structure of new compounds (or a citation to the published structure) must be given. The form used in calculating concentrations (e.g., base or salt) must be indicated.
d) Receptor Nomenclature: The nomenclature used to identify receptors and ion channels should conform to guidelines of the Committee on Receptor Nomenclature and Drug Classification of the International Union of Basic and Clinical Pharmacology (NC-IUPHAR).
Word 2007 users please note: With Word 2007, Microsoft has introduced a new proprietary math editor as the default editor for equations, but there are incompatibilities, which prevent us from using equations created with this new editor.
Note: Please use the Design Science Equation Editor (formerly the default Word editor) or Math Type rather than the new default math editor featured in the Insert ribbon. To use either Equation Editor or Math Type, in the Insert ribbon, click "Object" and choose object type "Microsoft Equation 3.0" or "Math Type Equation". The Equation Editor toolbar or Math Type window will appear and will work as in previous versions of Word.
Only material already published or in press may be cited in the reference list. References to unpublished observations, personal communications and papers submitted for publication are given in parentheses at the appropriate location in the text, not in the list of references. Only papers that have been officially accepted for publication may be cited as (''in press'') in the reference list. The authors are responsible for the accuracy of the references.
Please insert reference numbers into the text in parentheses [1, 2] and list references at the end of the chapter numerically. Use any number of references you wish, but obviously it will be helpful to readers if you list primarily important and new sources, and you do not need to document every minor point.
NB. The required style for references is that used in Journal of Internal Medicine!
References should be included as a numbered list in the order in which they appear in the text. Cite references in text using a number in parentheses placed on line (do not use superscript). Do not format references as endnotes. Include all the authors'' names (do not use "et al.") and complete article titles with inclusive pagination. Abbreviate the names of journals according to PubMed. Spell out the names of unlisted journals.
Please use the checklist before sending your chapter to the section''s editor:
- Title Page
Author''s/ authors'' full name(s) and the affiliations
7-to-10 key words
List of nonstandard abbreviations used in the text
E-mail address, phone and fax number of the corresponding author
- Conclusions or Conclusions and Clinical Implications
- Tables and Figures on separate pages, with legends