Glucocorticoid Signaling: From Molecules to Mice to Man

Glucocorticoid SignalingGlucocorticoid Signaling: From Molecules to Mice to Man (Advances in Experimental Medicine and Biology) is published by Springer; 1st ed. 2015 edition, and edited by Jen-Chywan Wang and Charles Harris.

Glucocorticoids, the steroid hormones secreted from the zona fasciculata of the adrenal cortex, play an important role in the maintenance of internal homeostasis by influencing activities of virtually all organs and tissues, such as the brain, liver, skeletal muscles and the immune-related organs and cells

Glucocorticoid Signaling: From Molecules to Mice to Man provides a comprehensive overview of glucocorticoids and their role in regulating many aspects of physiology and their use in the treatment of disease.

The book is broken into four sections that begin by giving a general introduction to glucocorticoids and a brief history of the field. The second section discusses the effects of glucocorticoids on metabolism, while the third section covers the effects of glucocorticoids on key tissues.

The final section addresses general topics, such as animal models in glucocorticoid research and clinical implications of glucocorticoid research. Featuring chapters from leaders in the field, this volume is of interest to both researchers and clinicians.

Some chapters are listed below:

  • Regulatory Actions of Glucocorticoid Hormones: From Organisms to Mechanisms
  • Molecular Biology of Glucocorticoid Signaling
  • Clinical Perspective: What Do Addison and Cushing Tell Us About Glucocorticoid Action?
  • How Do Glucocorticoids Regulate Lipid Metabolism?
  • Glucocorticoids and Skeletal Muscle
  • Glucocorticoid-Induced Osteoporosis
  • Effects of Glucocorticoids in the Immune System
  • Glucocorticoids and the Brain: Neural Mechanisms Regulating the Stress Response
  • Glucocorticoid Regulation of Reproduction
  • Glucocorticoids and the Lung
  • Glucocorticoids and the Cardiovascular System
  • Glucocorticoids and Cancer
  • Animal Models of Altered Glucocorticoid Signaling

Series: Advances in Experimental Medicine and Biology (Book 872); Hardcover: 385 pages; Publisher: Springer; 1st ed. 2015 edition (July 28, 2015)

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