Blogs

Short news & blogs covering the advance in neuroendocrine-immunology, neuroscience & immunology

Further Evidence That the Cytokine GM-CSF is an Essential Factor in the Pathogenesis of Multiple Sclerosis

Further Evidence That the Cytokine GM-CSF is an Essential Factor in the Pathogenesis of Multiple Sclerosis

Rasouli et al., published in the June 1st issue of the Journal of Immunology reports that treatment-naive MS patients had greater numbers of GM-CSF+ T cells in the peripheral blood, whereas CD4+ and CD8+ T cells in MS brain lesions expressed GM-CSF. In addition, interferon (INF)-β suppressed GM-CSF production by T cells, in vitro conditions. […]

Tumor Necrosis Factor Modulates Bitter Taste Responses

Tumor Necrosis Factor Modulates Bitter Taste Responses

A new study by Pu Feng and colleagues from the Monell Chemical Senses Center, Philadelphia, USA, published in Brain, Behavior, and Immunity indicates that tumor necrosis factor (TNF)-α, a major pro-inflammatory cytokine is involved in the regulation of bitter taste reception. Whether inflammatory cytokines contribute to taste reception or regulation is poorly understood. TNF is […]

New Function for Prolactin: Involvement in Sexual Behavior, Pair-Bonding and Infant Care

New Function for Prolactin: Involvement in Sexual Behavior, Pair-Bonding and Infant Care

Prolactin is well-known for its role in stimulating milk production in nursing mothers but a new study published in the online journal PLoS One identifies a previously unrecognized function of this hormone – its contribution to sexual behavior and pair-bonding. The study used cotton-top tamarins, a socially-monogamous, small monkey native to Colombia that live in […]

Optimism Linked To Better Cardiovascular Health

Optimism Linked To Better Cardiovascular Health

Rosalba Hernandez and colleagues from the University of Illinois at Urbana–Champaign, IL recently reported a link between optimism and cardiovascular health, derived from a large, ethnically and racially diverse population study, being perhaps the first in this field. Begun in 2000, the Multi-Ethnic Study of Atherosclerosis (MESA) included 6,000 people from six U.S. regions, followed […]

Deficiency of IL-10 in Chronic Fatigue Syndrome?

Deficiency of IL-10 in Chronic Fatigue Syndrome?

A new 2015 study, published in the Mediators of Inflammation journal suggests a deficiency of interleukin (IL)-10 in chronic fatigue syndrome (CFS). Chronic fatigue syndrome/myalgic encephalomyelitis, an illness characterized by unexplained fatigue lasting 6 months or more, is often linked to dysfunctional neuroendocrine and immune responses, including abnormal production of several cytokines (NG Klimas & […]

New Evidence Implicating IL-21 in Sjögren’s Syndrome

New Evidence Implicating IL-21 in Sjögren’s Syndrome

A study published in the journal Cornea provides new evidence that the pro-inflammatory cytokine interleukin (IL)-21 may contribute to the development and severity of Sjögren’s syndrome. Primary Sjögren’s syndrome is an autoimmune disease causing dry eyes and dry mouth, and featuring mononuclear and plasma cell infiltration in the salivary and lacrimal glands. Recent research indicates that […]

The Link between a Curvy Body, Newborns’ Brains and Breastfeeding: or Why Do Women Need Fat?

The Link between a Curvy Body, Newborns’ Brains and Breastfeeding: or Why Do Women Need Fat?

According to two recent reports in The Sunday Times and Daily Mail there is a good reason, from a human evolutionary perspective, why women may need fat and their curvy bodies. In line with the work of Will Lassek, and his research team from the University of Pittsburgh, Pennsylvania, discussed in these reports, the ‘fat […]

Childhood Adversities and the Development of Asthma in Adulthood

Childhood Adversities and the Development of Asthma in Adulthood

Recently the BMJ Open online journal published the first large-scale prospective, population-based study, involving 24 057 participants, followed for a 7-year period, documenting an association between childhood adversities and register-verified asthma diagnosis in adulthood. Previous research has shown that anxiety disorders and major depression are linked to asthma development, and two previous longitudinal studies reported […]

Long Term Use of Common Anticholinergic Drugs Linked To High Risk of Dementia

Long Term Use of Common Anticholinergic Drugs Linked To High Risk of Dementia

A new report published in JAMA Internal Medicine (formerly, Archives of Internal Medicine) indicates that cumulative anticholinergic medications exposure and use in the past 10 years is associated with a significantly increased risk for developing dementia. Common anticholinergic drugs include tricyclic antidepressants, first-generation antihistamines, and urinary bladder antispasmodics or some anti-vertigo drugs. In the JAMA […]

Women with Low Postpartum Oxytocin Levels Had Poor Bonding with Their Mothers and May Struggle to Bond with Their Babies

Women with Low Postpartum Oxytocin Levels Had Poor Bonding with Their Mothers and May Struggle to Bond with Their Babies

A new study by Valsamma Eapen and colleagues from University of New South Wales, Sydney, Australia found that women with low oxytocin levels in the postpartum have a history of bad mother-to-daughter bonding. The study is perhaps the first to show that women with reduced levels of oxytocin in the postpartum have higher subjective ratings […]