Blogs

Short news & blogs covering the advance in neuroendocrine-immunology, neuroscience & immunology

Th17 and Th22 Cells May Contribute To the Pathogenesis of Guillain-Barré Syndrome

Th17 and Th22 Cells May Contribute To the Pathogenesis of Guillain-Barré Syndrome

A study by Shujuan Li and colleagues from the Jilin University, Changchun, China, suggests that Th17 and Th22 cells might be involved in the onset and development of Guillain-Barré Syndrome. Guillain-Barré syndrome (GBS), described in 1916 by George Guillain, Jean-Alexandre Barré, and André Strohl, is an acute inflammatory immune-mediated polyradiculoneuropathy presenting typically with tingling, progressive […]

Personality Traits like Extraversion and Conscientiousness Linked to Pro-Inflammatory Genes Expression

Personality Traits like Extraversion and Conscientiousness Linked to Pro-Inflammatory Genes Expression

A study published in the journal Psychoneuroendocrinology demonstrates that leukocyte gene expression correlates with two major dimensions of human personality, extraversion and conscientiousness. A recent study in nonhuman primates provides new insights into the neuroanatomical basis of personality, showing that personality traits are linked to the anatomy of specific brain structures such as the anterior […]

An Association between Widespread Pain and Serum IL-8 Levels in Fibromyalgia Patients

An Association between Widespread Pain and Serum IL-8 Levels in Fibromyalgia Patients

Ozdolap S, et al. recently reported, at the European League against Rheumatism Annual European Congress of Rheumatology, June 10-13, 2015, a positive correlation between widespread pain and serum IL-8 in patients with fibromyalgia (FM). Fibromyalgia is characterized by widespread musculoskeletal pain accompanied by fatigue, sleep, memory and mood issues, and women are more likely to […]

Citations – Not Enough for an Academic Promotion – the Emerging Role of Popular Media Presence

Citations – Not Enough for an Academic Promotion – the Emerging Role of Popular Media Presence

In the contemporary world and academic life, citations might not be enough for an academic promotion. In their recent article, in the London School of Economics and Political Science Impact Blog,  Asit Biswas and Julian Kirchherr argue that the “impacts of most peer-reviewed publications even within the scientific community are miniscule”. They go on to say […]

Massage May Affect Immunity via the Sympathetic Innervation and Noradrenaline Release

Massage May Affect Immunity via the Sympathetic Innervation and Noradrenaline Release

Fulvio D`Acquisto and colleagues from Queen Mary University of London, UK recently showed that 8 days of massage-like therapy (hand- but not brush-stroked mice) resulted in modulation of murine immune system’s parameters through the sympathetic innervation and noradrenaline release. Massage per se apparently had no effect on anxiety-like behaviors in mice, but the immunomodulatory effects […]

Colchicine May Prove Useful In the Treatment of Acute Coronary Syndrome

Colchicine May Prove Useful In the Treatment of Acute Coronary Syndrome

A study by Gonzalo Martınez et al., published in the Journal of the American Heart Association indicates that colchicine may also be useful for the treatment of heart attacks by reducing cardiac inflammation and the local pro-inflammatory cytokine production. Colchicine is an alkaloid with potent anti-inflammatory effects, which is often used for the treatment of […]

Early Childhood Farm Environment Exposure Inducing T Helper 1-Cytokine Profiles and Asthma Protection?

Early Childhood Farm Environment Exposure Inducing T Helper 1-Cytokine Profiles and Asthma Protection?

In a recent study by Heidi Kääriö et al., using samples from the Protection Against Allergy-Study in Rural Environments (PASTURE) birth cohort, demonstrate that farm exposures (stables, hay barn, farm milk) at age 4.5 years is linked to amplified Th1-type cytokine production. The research group from Finland and Germany report that peripheral blood mononuclear cells […]

High Levels of the Pro-Inflammatory Cytokines IL-1β and IL-6 Found in Patients with Suicidality

High Levels of the Pro-Inflammatory Cytokines IL-1β and IL-6 Found in Patients with Suicidality

A recent  study published in the journal Biological Psychiatry indicates the presence of aberrant cytokine levels in patients with suicidality, and identifies a link between pro-inflammatory cytokines, and specifically, interleukin (IL)-1β and IL-6 with suicidal behavior. Previous research has shown that major depression is associated with an immune response with an increased production of pro-inflammatory […]

Sex and Stem cells

Sex and Stem cells

A new study in Cell Stem Cell, discusses the “sexual dimorphism of longevity”, wherein most of supercentenarians are female, linking this to increased stem cell self-renewal and regeneration potential in females. Of note, out of the 53 living supercentenarians – human individuals currently living over the age of 110 – 51 are female, and sexual […]

Further Evidence That the Cytokine GM-CSF is an Essential Factor in the Pathogenesis of Multiple Sclerosis

Further Evidence That the Cytokine GM-CSF is an Essential Factor in the Pathogenesis of Multiple Sclerosis

Rasouli et al., published in the June 1st issue of the Journal of Immunology reports that treatment-naive MS patients had greater numbers of GM-CSF+ T cells in the peripheral blood, whereas CD4+ and CD8+ T cells in MS brain lesions expressed GM-CSF. In addition, interferon (INF)-β suppressed GM-CSF production by T cells, in vitro conditions. […]